Unveiling Novel One-Pot Synthesised Polyaniline-Pyrazole: Electrical Conductivity and Antimicrobial Investigations
Archana Srivastava1, Chetna Kumari1, John Andrews Staline C1
1Department of Chemistry, Banasthali Vidyapith, Banasthali, Rajasthan, India.
Chemistry & Biodiversity
|March 27, 2026
Summary
Researchers synthesized polyaniline-pyrazole (PANI-Pyz) copolymer and evaluated its antimicrobial properties. The PANI-Pyz copolymer demonstrated enhanced antibacterial and antifungal activity against various pathogens compared to polyaniline alone.
Area of Science:
- Polymer Chemistry
- Materials Science
- Microbiology
Background:
- Polyaniline (PANI) is a conductive polymer with potential applications.
- Developing novel copolymers can enhance material properties.
- Assessing antimicrobial activity is crucial for new material development.
Purpose of the Study:
- To synthesize a novel polyaniline-pyrazole (PANI-Pyz) copolymer.
- To characterize the synthesized PANI-Pyz copolymer.
- To evaluate the antimicrobial efficacy of PANI-Pyz against bacterial and fungal strains.
Main Methods:
- Synthesis of polyaniline and polyaniline-pyrazole copolymer.
- Characterization using UV-visible, FTIR, TGA, viscosity, BET, and conductivity measurements.
- Antimicrobial activity testing using minimum inhibitory concentration (MIC) and IC50 assays.
Main Results:
- The PANI-Pyz copolymer was successfully synthesized and characterized.
- PANI-Pyz exhibited significant antibacterial activity against S. aureus, B. subtilis, E. coli, and P. aeruginosa.
- PANI-Pyz showed enhanced antifungal activity against P. chrysogenum and A. niger compared to PANI.
Conclusions:
- The synthesized PANI-Pyz copolymer possesses superior antimicrobial properties.
- PANI-Pyz is a promising material for applications requiring antimicrobial activity.
- Copolymerization with pyrazole significantly enhances the antimicrobial efficacy of polyaniline.
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