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Related Experiment Video

Updated: Mar 28, 2026

Application of a New Mesh Fixation Method in Laparoscopic Incisional Hernia Repair
05:15

Application of a New Mesh Fixation Method in Laparoscopic Incisional Hernia Repair

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Prophylactic Mesh Reinforcement Versus Primary Suture for Midline Laparotomy Closure: An Updated Systematic Review

Marwan Ibrahim1, Ali Alseneid2, Mara Mijatovic3

  • 1Department of General Surgery, Milton Keynes University Hospital, Milton Keynes, GBR.

Cureus
|March 27, 2026
PubMed
Summary
This summary is machine-generated.

Prophylactic mesh reinforcement significantly lowers incisional hernia risk after midline laparotomy compared to sutures. This approach appears safe, potentially improving long-term abdominal wall outcomes for patients.

Keywords:
abdominal wall closureelective laparotomyincisional hernia preventionincisional hernia repairmeta-analysismidline laparotomyprophylactic meshsystematic review

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Area of Science:

  • Abdominal Surgery
  • Surgical Complications
  • Biomaterials in Medicine

Background:

  • Incisional hernias are frequent after midline laparotomy.
  • Preventive mesh use is debated due to complication concerns.

Purpose of the Study:

  • To systematically review and meta-analyze randomized controlled trials (RCTs).
  • To compare prophylactic mesh versus suture closure for incisional hernia prevention.

Main Methods:

  • Systematic review and meta-analysis following PRISMA 2020 guidelines.
  • Searched RCTs comparing mesh reinforcement with primary suture closure.
  • Pooled data using fixed-effects meta-analysis for incisional hernia incidence.

Main Results:

  • Four RCTs (1,006 patients) analyzed.
  • Prophylactic mesh reduced incisional hernia incidence (RR 0.39, CI 0.27-0.57).
  • No clear increase in significant wound morbidity observed.

Conclusions:

  • Prophylactic mesh significantly decreases incisional hernia risk post-laparotomy.
  • Mesh reinforcement is not clearly associated with increased complications.
  • Selective mesh use may benefit high-risk patients; further studies needed.