Related Experiment Video
Updated: Mar 28, 2026
An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
Published on: February 8, 2019
GAL and F2R as immune diagnostic biomarkers for fetal growth restriction
Shiying Chen1, Yumin Ke1, Zhimei Zhou1
1Department of Gynecology and Obstetrics, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian 362000, China.
Abstract:
Fetal growth restriction (FGR) is associated with adverse perinatal outcomes, but reliable diagnostic biomarkers are lacking. Through bioinformatics analysis of public datasets and clinical validation, we identified GAL and F2R as potential immune-related biomarkers associated with FGR. Both genes were consistently upregulated in FGR tissues and correlated with altered immune cell infiltration. These findings suggest that GAL and F2R may serve as diagnostic markers and potential therapeutic targets for FGR, facilitating early intervention and improved neonatal outcomes.
