Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Support in Decision-Making for All.

Jasmine Gunkel1,2, David Wasserman3, Leslie Francis4

  • 1Department of Philosophy, https://ror.org/01cwqze88National Institutes of Health, United States.

The Journal of Law, Medicine & Ethics : a Journal of the American Society of Law, Medicine & Ethics
|March 27, 2026
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same authorSame journal

Intellectual Disability and Supported Decision-Making in Clinical Research: Anticipating Ethical Challenges.

The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics·2026
Same author

Supported Decision-Making for Clinical Research Participants with Mental Illness.

The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics·2026
Same author

The importance of residual newborn screening dried blood spots, 2025 revision: A position statement of the American College of Medical Genetics and Genomics (ACMG).

Genetics in medicine : official journal of the American College of Medical Genetics·2025
Same author

Person-Affecting Reasons for Prenatal Gene-Editing?

The American journal of bioethics : AJOB·2024
Same author

The Overlooked Risk of Intimate Violation in Research: No Perianal Sampling Without Consent.

The American journal of bioethics : AJOB·2024
Same author

Microvascular insulin resistance associates with enhanced muscle glucose disposal in CD36 deficiency.

medRxiv : the preprint server for health sciences·2024
Same journal

Prohibited AI Practices in Healthcare under the European Artificial Intelligence Act.

The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics·2026
Same journal

Probing the Prevalence of Pharmaceutical Corruption.

The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics·2026
Same journal

Regulatory Guidance for the Return of Raw Genomic Data to Research Participants: A Qualitative Interview Study.

The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics·2026
Same journal

Supported Decision-Making and the Inclusion of People who Lack Decisional Capacity in Greater than Minimal Risk Research.

The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics·2026
Same journal

Using Supported Decision-Making to Promote Value-Aligned Research Participation.

The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics·2026
See all related articles

Supported decision-making empowers individuals to make their own choices, shifting from surrogate decision-making. This approach should be standard for all clinical trial enrollment, especially for high-risk research.

Area of Science:

  • Bioethics
  • Disability Rights
  • Clinical Trial Ethics

Background:

  • Surrogate decision-making is the traditional legal standard for individuals lacking decision-making capacity.
  • Supported decision-making empowers individuals to make their own choices with assistance.
  • Disability rights advocates have long argued for the ethical and legal basis of supported decision-making.

Purpose of the Study:

  • To advocate for a paradigm shift in clinical trial enrollment norms.
  • To propose "support in decision-making for all" for research protocols exceeding a specific risk threshold.
  • To explore the benefits of universal support in decision-making for clinical trial participants.

Main Methods:

  • Drawing inspiration from universal design principles.
Keywords:
autonomydisability rightsinformed consentresearch ethicssupported decision-making

Related Experiment Videos

  • Incorporating feminist insights on autonomy.
  • Arguing for a presumption of support in decision-making.

    • Main Results:

    • Supported decision-making offers significant expressive and practical advantages.
    • Presuming support enhances autonomy for all potential research participants.
    • This approach leads to more informed and autonomous enrollment decisions.

    Conclusions:

    • A universal approach to supported decision-making in clinical trials is ethically and practically beneficial.
    • Shifting norms towards support empowers all participants, particularly in high-risk research.
    • Supported decision-making aligns with principles of autonomy and universal design.