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Anatomy of the Genitourinary System II: Bladder and Urethra01:19

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The lower urinary system consists of the urinary bladder and urethra, which are essential in storing and expelling urine from the body. Together with the internal and external sphincters, these structures work together to regulate urination effectively.Anatomy of the BladderThe urinary bladder is a muscular, stretchable organ behind the pubic bone and in front of the rectum. In females, the bladder is positioned anterior to the vagina and inferior to the uterus, while in males, it is located...
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Transurethral Resection of the Prostate in Patients With Neurogenic Lower Urinary Tract Dysfunction.

Anjali Shekar1, Iyla Bagheri1, Nicole Sherman1

  • 1Department of Urology, Northwell Health, New Hyde Park, New York, USA.

Neurourology and Urodynamics
|March 27, 2026
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Summary

Transurethral resection of the prostate (TURP) is effective for benign prostatic hyperplasia but requires careful selection in neurogenic lower urinary tract dysfunction (NLUTD). Urodynamic evaluation is crucial for optimizing TURP outcomes in NLUTD patients.

Keywords:
benign prostatic hyperplasialower urinary tract symptomsneurogenic urinary bladdertransurethral resection of prostateurodynamics

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Area of Science:

  • Urology
  • Neurology
  • Surgical Outcomes

Background:

  • Transurethral resection of the prostate (TURP) is the standard surgical treatment for benign prostatic hyperplasia (BPH).
  • Its application in men with neurogenic lower urinary tract dysfunction (NLUTD) presents challenges due to diverse neurological conditions and variable bladder/sphincter function.

Purpose of the Study:

  • To evaluate the outcomes of TURP in men diagnosed with NLUTD.
  • To assess the role of urodynamic evaluation in patient selection for TURP in this population.

Main Methods:

  • A narrative literature review was conducted using PubMed and reference lists.
  • Studies included patients with conditions like spinal cord injury, spina bifida, stroke, multiple sclerosis, and Parkinson's disease.
  • Focus was on functional outcomes and urodynamic predictors.

Main Results:

  • TURP outcomes in NLUTD patients are highly variable, depending on the specific neurological condition and bladder/sphincter function.
  • Preoperative urodynamic evaluation is essential for identifying suitable candidates and minimizing risks like incontinence or retention.
  • Preserved detrusor contractility and the presence of bladder outlet obstruction are key factors.

Conclusions:

  • TURP in men with NLUTD should be considered selectively.
  • Objective urodynamic findings are critical for guiding surgical decisions and predicting potential benefits and risks.
  • Baseline detrusor function and bladder outlet obstruction significantly influence TURP success in NLUTD.