Mandibular Reconstruction Using Masquelet Induced Membrane Technique and Implant Rehabilitation

Area of Science:

• Oral and Maxillofacial Surgery
• Regenerative Medicine
• Biomaterials Engineering

Background:

• Infected mandibular fracture nonunion presents a significant reconstructive challenge.
• Conventional treatments often face limitations in achieving both infection control and bone regeneration.

Purpose of the Study:

• To present a case of infected mandibular fracture nonunion managed with the Masquelet induced membrane technique (MIMT).
• To evaluate the efficacy of MIMT followed by implant-supported dental rehabilitation.

Main Methods:

• A three-stage surgical protocol involving debridement, spacer implantation, defect reconstruction with bone graft, and delayed implant placement.
• Utilized a polymethyl methacrylate spacer to induce a membrane for guiding bone regeneration.

Main Results:

• Successful reconstruction of the mandibular defect with regenerated bone suitable for dental implants.
• Achieved satisfactory osseointegration of all placed implants without infection recurrence.
• Restored masticatory function and mandibular contour.

Conclusions:

• The Masquelet induced membrane technique is a viable option for managing complex infected mandibular defects.
• MIMT provides a robust biological scaffold for successful dental implant rehabilitation in oral and maxillofacial reconstruction.