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Identification of Cyclin-dependent Kinase 1 Specific Phosphorylation Sites by an In Vitro Kinase Assay
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Protein Kinase D2 Regulates GRASP65 Phosphorylation and Golgi Ribbon Unlinking During G2/M Transition

Inmaculada Ayala1, Daniela Spano1, Antonino Colanzi1

  • 1Institute of Endotypes in Oncology, Metabolism and Immunology "G. Salvatore" (IEOMI), National Research Council (CNR), Via P. Castellino 111, 80131 Naples, Italy.

Cells
|March 27, 2026
PubMed
Summary

Protein kinase D2 (PKD2) regulates Golgi ribbon unlinking by phosphorylating GRASP65, a key step for cell division. This discovery clarifies Golgi disassembly during the G2/M transition.

Keywords:
GRASP65Golgi complexPKDcell cycle

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