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Antimicrobial Stewardship Programs in Chile: A Historical Overview.

Mirta Acuña1,2,3,4, Tania Herrera5, Dona Benadof1,2,3,4

  • 1Hospital Roberto del Rio, Santiago 8380457, Chile.

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Summary
This summary is machine-generated.

Antimicrobial Stewardship Programs (ASPs) combat antimicrobial resistance (AMR) by optimizing drug use. Chile has made progress in implementing national ASP policies across various sectors, though challenges remain.

Keywords:
Chileantimicrobial stewardship programhealth policieshistory

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Area of Science:

  • Public Health
  • Infectious Diseases
  • Health Policy

Background:

  • Antimicrobial resistance (AMR) is a global health threat driven by inappropriate antimicrobial use.
  • Antimicrobial Stewardship Programs (ASPs) are critical for optimizing antimicrobial therapy and mitigating AMR.
  • Effective ASP implementation requires a multidisciplinary approach and adaptation to local contexts.

Purpose of the Study:

  • To review the development and evolution of Chile's national antimicrobial stewardship policy.
  • To analyze progress and persistent challenges in national ASP implementation in Chile.

Main Methods:

  • Narrative review of publications indexed in SciELO.
  • Analysis of official documents from the Ministry of Health (MINSAL).
  • Review of relevant national legislation.

Main Results:

  • Chilean antimicrobial stewardship initiatives began in the late 1990s with regulatory measures.
  • Progress includes expanded ASP coverage, strengthened regulations, national surveillance, and stewardship indicators.
  • Advances have been made in hospital, primary care, veterinary, and aquaculture settings.

Conclusions:

  • Chile has achieved substantial progress in developing and implementing its national antimicrobial stewardship policy.
  • Challenges in workforce capacity, technological infrastructure, and long-term monitoring need to be addressed for further consolidation.