Related Experiment Video
Updated: Mar 29, 2026
05:31
Murine Model of Thoracic Aortic Dissection Induced by Oral β-Aminopropionitrile and Subcutaneous Angiotensin II Infusion
Published on: May 16, 2025
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Association Between Diet Quality, Physical Activity, and the Risk of Aortic Dissection-A Prospective Cohort Study.
Zahra Parvan1, Yasmin Soltanzadeh-Naderi1, Stefan Acosta1,2
1Department of Clinical Sciences, Lund University, 214 21 Malmö, Sweden.
Journal of Cardiovascular Development and Disease
|March 27, 2026
Summary
This study found no link between diet quality or physical activity and aortic dissection (AD) risk. Controlling hypertension and quitting smoking are crucial for preventing AD.
Area of Science:
- Cardiovascular research
- Epidemiology
- Public health
Background:
- Hypertension and smoking are established risk factors for aortic dissection (AD).
- The influence of other lifestyle factors, such as diet and physical activity, on AD risk remains unclear.
Purpose of the Study:
- To investigate the association between diet quality, physical activity, and the risk of developing aortic dissection (AD).
Main Methods:
- Utilized data from 28,094 participants in the Malmö Diet and Cancer Study, with follow-up through national health registers.
- Assessed diet quality using a six-component Diet Quality Index and identified incident AD via ICD codes.
- Employed Cox proportional hazards models to analyze associations between lifestyle factors and AD risk.
Main Results:
- Over a median follow-up of 26.6 years, 130 cases of AD occurred.
- Independent risk factors for AD included higher age, male sex, hypertension, and current smoking.
- No significant associations were observed between diet quality or physical activity and the risk of AD.
Conclusions:
- Diet quality and physical activity do not appear to be significantly associated with AD risk.
- Effective blood pressure control and smoking cessation are identified as primary preventive strategies for reducing AD incidence.
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