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LTPNet: Lesion-Aware Triple-Path Feature Fusion Network for Skin Lesion Segmentation
Yange Sun1,2, Sen Chen1,2, Huaping Guo1,2
1School of Computer and Information Technology, Xinyang Normal University, Xinyang 464000, China.
Journal of Imaging
|March 27, 2026
Summary
A new deep learning model, the lesion-aware triple-path feature fusion network (LTPNet), improves skin lesion segmentation accuracy. This advanced method enhances clinical decision support by overcoming challenges like complex backgrounds and low contrast.
Area of Science:
- Medical image analysis
- Computer vision
- Artificial intelligence in healthcare
Background:
- Accurate skin lesion segmentation is crucial for diagnosis but challenged by complex backgrounds, ambiguous boundaries, and low contrast.
- Existing methods struggle with precise delineation, necessitating advanced deep learning approaches.
Purpose of the Study:
- To introduce the lesion-aware triple-path feature fusion network (LTPNet) for improved skin lesion segmentation.
- To address limitations in current segmentation techniques by enhancing feature extraction, refinement, and aggregation.
Main Methods:
- The proposed LTPNet framework utilizes an end-to-end approach with distinct extraction, refinement, and aggregation stages.
- Key modules include general foreground-background attention, attentive spatial modulator (ASM), lesion-aware lite-gate attention (LALGA), and triple-path feature fusion (TPFF).
- TPFF employs common, saliency, and difference paths to model multi-scale feature relationships.
Main Results:
- LTPNet demonstrated superior segmentation accuracy on both in-domain and cross-domain datasets.
- The model achieved competitive results with reasonable inference efficiency and manageable model complexity.
- Experiments confirmed the effectiveness of the proposed attention and fusion modules in enhancing segmentation performance.
Conclusions:
- LTPNet offers an effective solution for accurate and reliable skin lesion segmentation.
- The proposed network shows significant potential for clinical decision support systems.
- The lesion-aware design and multi-path fusion strategy contribute to robust performance across diverse datasets.