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Should Every Symptomatic Patient with Mushroom Poisoning Be Monitored in the Intensive Care Unit?-A Retrospective
Duygu Kayar Calili1, Demet Bolukbasi2, Serife Gokbulut Bektas3
1Department of Anesthesiology and Reanimation-Intensive Care, Faculty of Medicine, Ankara Yıldırım Beyazıt University, Ankara Bilkent City Hospital, Ankara 06800, Turkey.
Toxins
|March 27, 2026
Summary
Early diagnosis of fatal mushroom poisoning is lacking. This study suggests reserving intensive care unit (ICU) admission for severe cases, particularly those with acute liver failure, to optimize resource use.
Area of Science:
- Toxicology
- Clinical Medicine
- Critical Care
Background:
- No rapid diagnostic methods exist for fatal mushroom poisoning.
- Symptomatic patients are often admitted to intensive care units (ICUs) for monitoring and treatment.
Purpose of the Study:
- Evaluate clinical and laboratory trends in ICU patients with mushroom poisoning.
- Assess treatment characteristics and outcomes.
- Determine the necessity of level 3 ICU admission for all symptomatic cases.
Main Methods:
- Retrospective study of 54 ICU patients with mushroom poisoning.
- Analysis of clinical data, laboratory values, treatment, and outcomes.
- Comparison of laboratory values upon admission and discharge.
Main Results:
- The overall mortality rate was 5.6%, with 7% developing acute liver failure (ALF).
- Significant improvements in liver enzymes, bilirubin, renal function markers, and coagulation parameters were observed from admission to discharge (p < 0.05).
- Two patients required liver transplantation, with one fatality.
Conclusions:
- Mushroom poisoning patients at risk of ALF should be considered for early transfer to transplant centers.
- Level 3 ICU monitoring and treatment should be prioritized for patients progressing to liver failure, not all symptomatic cases, to ensure effective resource allocation.
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