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Automated Longitudinal Quantification of Retinal and Choroidal Vascular Changes After Phacoemulsification
Seung Hoon Lee1, Phil Kyu Lee1, Se Eun Park1
1Department of Ophthalmology, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, #327 Sosa-ro, Wonmi-gu, Bucheon 14647, Gyeonggi-do, Republic of Korea.
Tomography (Ann Arbor, Mich.)
|March 27, 2026
Summary
Phacoemulsification impacts retinal and choroidal vasculature, with automated OCTA revealing layer-specific changes. These vascular responses are influenced by clinical factors like anesthesia and sex.
Area of Science:
- Ophthalmology
- Vascular Biology
- Medical Imaging
Background:
- Phacoemulsification is a common cataract surgery.
- Understanding its impact on ocular vasculature is crucial.
- Automated optical coherence tomography angiography (OCTA) offers detailed vascular analysis.
Purpose of the Study:
- To evaluate longitudinal changes in retinal and choroidal vasculature after phacoemulsification.
- To identify clinical factors influencing these vascular changes.
- To utilize automated OCTA for quantitative analysis.
Main Methods:
- Retrospective study of 26 subjects (31 eyes) undergoing phacoemulsification.
- OCTA performed at multiple postoperative time points (1 day to 2 months).
- Automated analysis of superficial capillary plexus (SCP), deep capillary plexus (DCP), choriocapillaris, and Haller layer; statistical analysis of changes and influencing factors.
Main Results:
- Significant increases in vessel density and length in SCP and DCP post-surgery.
- No significant changes in choriocapillaris parameters.
- Decreased vessel diameter in the Haller layer.
- Correlations observed between adjacent vascular layers.
- Retrobulbar anesthesia and sex modulated choroidal vascular changes.
Conclusions:
- Automated OCTA reveals layer-dependent vascular responses in retina and choroid after phacoemulsification.
- Vascular changes are coordinated between adjacent layers.
- Clinical factors selectively influence these vascular alterations.
