Use of Alternative Endograft for Popliteal Artery Aneurysm Endovascular Repair: A Single Center Experience in Italy...

To describe clinical outcomes associated with the off-label use of the Wrapsody™ Cell-Impermeable Endoprosthesis (CIE) for endovascular popliteal artery aneurysm (PAA) repair.

This was a retrospective analysis of patients with PAA treated (September 2021-October 2024) with the WRAPSODY CIE. Clinical outcomes of interest included successful device placement, complete exclusion of the aneurysm at 30 days, aneurysm shrinkage, primary patency, reintervention with secondary patency, and complications. Patients were followed for a range of 4-48 months.

Eighteen patients were analyzed (17 males and 1 female). The mean age of patients treated was 73 years. The mean aneurysm length was 6.8 cm. All devices were successfully placed, no major complications were observed. Aneurysm shrinkage was achieved in 8 patients. One patient presented a small type II endoleak from a genicular artery. Early primary patency at 4 months was 100%, late patency at 16 months was 85.7%. One patient underwent endovascular reintervention for acute intrastent thrombosis 12 months postprocedure, without the possibility of recanalization and secondary patency. Another endograft occluded chronically, without symptoms; therefore, the patient was treated with medical therapy.

These results indicate that the WRAPSODY CIE used may be a safe and effective intervention for endovascular popliteal artery aneurysm repair and may help physicians optimize care for PAA.