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Biochemical Measurement of Neonatal Hypoxia
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Fibroblast growth factor 21 and growth differentiation factor 15 as biomarkers for oxidative stress in children with

Maha A Abd Elbaky1, Mohamed Shehata1, Khalil Abdelkhalek2

  • 1Department of Clinical and Chemical Pathology, Faculty of Medicine, Cairo University, Cairo, Egypt.

BMC Pediatrics
|March 28, 2026
PubMed
Abstract

No abstract available in PubMed .

Keywords:
FGF21GDF15GlutathioneOrganic acidemiaOxidative stress

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Role of Hematopoietic Growth Factors01:28

Role of Hematopoietic Growth Factors

Hematopoietic growth factors are molecules that regulate the differentiation rate of hematopoietic stem cells (HSCs). Erythropoietin (EPO), primarily produced by the kidneys, plays a crucial role in erythrocyte production. When oxygen levels in the blood are low, EPO is released into the bloodstream, reaching the bone marrow, where it stimulates HSCs to differentiate and mature into erythrocytes, which are vital for oxygen transport.
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