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CIRCLE-F/V: a dual-mode CRISPR-Cas13a cascade biosensor for ultrasensitive and visual detection of low-abundance EGFR

Tao Zhu1, Zixuan Wang2, Yingyu Wu1

  • 1School of Public Health, Health Science Center, Ningbo University, 818 Fenghua Road, Ningbo, Zhejiang Province, 315211, People's Republic of China.

Journal of Biological Engineering
|March 28, 2026
PubMed
Abstract

No abstract available in PubMed .

Keywords:
BiosensorCRISPR-Cas13a systemDumbbell-triggered cascade amplificationEGFR L858R mutationFluorescenceLateral flow assay

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