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The Impact of Follow-Up on Etiological Classification of Pediatric Vertigo
Nina Božanić Urbančič1,2, Dejan Mladenov1, Saba Battelino1,2
1Department of Otorhinolaryngology and Cervicofacial Surgery, University Medical Centre Ljubljana, Zaloška cesta 2, 1000 Ljubljana, Slovenia.
Insights
Extended follow-up significantly improves the diagnosis of vertigo and dizziness in children. This approach reduces diagnostic uncertainty and optimizes the use of investigations for pediatric vertigo.
Area of Science:
- Pediatric Otolaryngology
- Neurology
- Vestibular Disorders
Background:
- Vertigo and dizziness in children present diagnostic challenges with diverse causes.
- Many pediatric patients lack a definitive diagnosis upon initial evaluation.
- Limited evidence exists on the impact of long-term follow-up for classifying pediatric vertigo etiologies.
Purpose of the Study:
- To reassess the etiological classification of pediatric vertigo and dizziness using extended follow-up data.
- To evaluate the impact of longitudinal follow-up on diagnostic accuracy in pediatric vertigo.
- To compare etiological distributions before and after extended follow-up.
Main Methods:
- Observational cohort study with prospectively collected data from children aged 1-17 years.
- Retrospective revision of a previously published cohort, incorporating extended follow-up data up to 2025.
- Descriptive statistics to compare etiological classifications at initial presentation versus after extended follow-up.
Main Results:
- The proportion of unclassified etiologies decreased from 44% to 10% after extended follow-up.
- Identified etiologies included central (35%), peripheral vestibular (18%), hemodynamic (16%), and psychogenic (10%).
- Extended follow-up averaged 17.6 months, revealing low diagnostic yield for certain tests like cranial CT.
Conclusions:
- Extended follow-up substantially enhances etiological classification in pediatric vertigo and dizziness.
- Initial diagnostic uncertainty often stems from evolving clinical presentations, not a lack of underlying pathology.
- A longitudinal, multidisciplinary approach is crucial for accurate diagnosis and optimized investigation use in pediatric vertigo.
Abstract:
Background: Vertigo and dizziness in children represent diagnostically challenging conditions with heterogeneous etiologies. At initial presentation, a substantial proportion of pediatric patients remain without a definitive etiological diagnosis. Evidence on the impact of longitudinal follow-up on etiological classification in pediatric vertigo is limited. Methods: This observational cohort study uses prospectively collected clinical data. Children aged 1-17 years who presented to a tertiary ENT clinic with vertigo and/or dizziness between 2015 and 2020 were systematically enrolled and followed. The present study represents a retrospective revision of a previously published cohort of 257 children. In 2025, extended follow-up data were reviewed to reassess etiological classification using the same diagnostic categories as in the original analysis. Descriptive statistics were applied to compare etiological distributions at initial evaluation and after follow-up revision. Results: After data revision, the proportion of children with unclassified etiology decreased from 44% to 10%. Central etiologies accounted for 35% of cases, peripheral vestibular disorders for 18%, hemodynamic causes for 16%, psychogenic etiologies for 10%, and other specific causes for 7%. Follow-up duration ranged from 0 to 132 months (mean 17.6 months; median 4.5 months). Diagnostic investigations were frequently performed; however, the etiological yield of certain tests, particularly cranial computed tomography, was low. Conclusions: Extended follow-up significantly improves etiological classification in children with vertigo and dizziness, demonstrating that diagnostic uncertainty at initial presentation often reflects evolving clinical phenotypes rather than the absence of an underlying disorder. A longitudinal, clinically guided, and multidisciplinary approach is essential to enhance diagnostic accuracy and optimize the use of diagnostic investigations in pediatric vertigo.
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