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Updated: Mar 29, 2026

Frailty Assessment in an Aging Mouse Model
Published on: September 23, 2025
Comparison of Frailty and Autonomy Levels in Older Adults According to Place of Residence
Andrea Machado1, Pedro Forte2,3,4, Filipe Rodrigues1,5
1ESECS-Polytechnic of Leiria, 2411-901 Leiria, Portugal.
Abstract:
Background/Objectives: The present study aimed to compare levels of frailty and functional independence in older adults according to their place of residence and to analyze the associations between age, frailty, and autonomy, considering sex. Methods: A cross-sectional analytical study was conducted with a sample of 77 older adults (80.16 ± 8.68 years), divided into community-dwelling (n = 38) and institutionalized (n = 39) participants. Data collection included sociodemographic characterization and the assessment of frailty and autonomy. Results: Older adults in the community showed significantly higher levels of autonomy (94.21 ± 10.81) compared to those who were institutionalized (75.53 ± 23.21; p < 0.001). No significant differences were found in frailty levels between the groups (p = 0.674). Correlation analysis revealed a strong negative association between frailty and autonomy, which was more pronounced in institutionalized older adults (r = -0.64) and in males (r = -0.72). Age was only correlated with the loss of autonomy in men (r = -0.43). Conclusions: Place of residence is a critical determinant of functional autonomy but not of perceived frailty. The results highlight a health-survival paradox, where men exhibit a more abrupt functional decline associated with frailty. The implementation of gerontomotricity programs in residential care facilities is suggested to mitigate learned dependency.
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