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Updated: Mar 29, 2026
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Semi-quantitative Assessment Using [18F]FDG Tracer in Patients with Severe Brain Injury
Published on: November 9, 2018
Left Pulvinar Thalamic Tumor with Ventricular Atrial Extension Presenting as Network-Level Cognitive and Gait
Florin Mihail Filipoiu1,2, Stefan Oprea1,2, Cosmin Pantu1,2
1Faculty of General Medicine, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Deep thalamic tumors can cause significant cognitive and motor deficits by affecting brain networks. A novel physiology-guided surgical approach successfully improved patient function and demonstrated early identification of deep network pathology.
Area of Science:
- Neurosurgery
- Neurology
- Neuroscience
Background:
- Deep thalamic and periventricular lesions are rare in adults but can lead to substantial functional loss.
- These lesions impact thalamocortical regulation, periventricular white matter tracts, and ventricular compliance, causing executive dysfunction, language deficits, and gait instability.
- Early identification of subtle screening deficits is challenging, and autonomic symptoms may appear late.
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