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MEWDS-like Presentation Unmasking Sequential Bilateral Multifocal Choroiditis: Insights from Longitudinal Multimodal
Blerta Lang1, Annekatrin Rickmann1, Karl Thomas Boden1
1Eye Clinic Sulzbach, Knappschaft Hospitals Saar, An der Klinik 10, D-66280 Sulzbach, Germany.
Biomedicines
|March 28, 2026
Summary
This case study shows how multimodal imaging over time can distinguish Multiple Evanescent White Dot Syndrome (MEWDS)-like presentations from sequential bilateral Multifocal Choroiditis (MFC)/Punctate Inner Choroidopathy (PIC) spectrum disease.
Area of Science:
- Ophthalmology
- Medical Imaging
- Rheumatology
Background:
- Multiple Evanescent White Dot Syndrome (MEWDS) is typically acute and self-resolving.
- Multifocal Choroiditis (MFC) and Punctate Inner Choroidopathy (PIC) are relapsing inflammatory eye conditions.
- Diagnostic overlap between MEWDS and MFC/PIC can complicate early identification, necessitating longitudinal multimodal imaging.

