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Related Concept Videos

Heart Failure III: Clinical Manifestations01:26

Heart Failure III: Clinical Manifestations

846
Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
846
Heart Failure V: Medical Management01:30

Heart Failure V: Medical Management

520
Medical Management of Acute Decompensated Heart Failure (ADHF)The primary goals of therapy for patients hospitalized with acute decompensated heart failure (ADHF) include:Relieving symptomsOptimizing volume statusSupporting oxygenation and ventilationMaintaining cardiac output (CO) and end-organ perfusionIdentifying and addressing the cause of ADHFPreventing complicationsProviding patient education on factors precipitating HF exacerbationPlanning for dischargeOngoing monitoring and assessment...
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Imbalances in Cardiac Output01:26

Imbalances in Cardiac Output

3.4K
The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
3.4K
Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

4.5K
Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
4.5K
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

1.4K
Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
1.4K
Heart Failure VI: Adjunct Therapies01:22

Heart Failure VI: Adjunct Therapies

547
Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
547

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Related Experiment Video

Updated: Mar 29, 2026

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
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Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure

Published on: June 10, 2025

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Increased Mortality and Complication Rates in Weekend Admissions for Acute Decompensated Heart Failure: A Five-Year

Hadi Itani1, Mohammad Ennab1, Mohamad Bahij Moumneh1

  • 1Department of Internal Medicine, Staten Island University Hospital, Northwell Health, New Hyde Park, NY 10305, USA.

Journal of Clinical Medicine
|March 28, 2026
PubMed
Summary

Hospital admissions for acute decompensated heart failure (ADHF) on weekends are linked to higher mortality and complication risks. Standardized care protocols are needed to ensure equitable treatment for all patients, regardless of admission timing.

Keywords:
acute decompensated heart failureacute kidney injurycardiac arrestmortalityrespiratory failureweekdayweekend

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Author Spotlight: Unveiling Prognostic Indicators in Heart Failure - The Role of Phase Angle and Bioelectrical Impedance Analysis
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Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
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Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
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Author Spotlight: Unveiling Prognostic Indicators in Heart Failure - The Role of Phase Angle and Bioelectrical Impedance Analysis
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Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
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Area of Science:

  • Cardiology
  • Health Services Research
  • Public Health

Background:

  • The

Purpose of the Study:

  • To investigate the

Main Methods:

  • A retrospective cohort study utilized the 2016-2020 Nationwide Inpatient Sample (NIS).
  • Adult acute decompensated heart failure (ADHF) admissions were identified and classified as weekend or weekday.
  • Propensity score matching (1:1) was applied to compare outcomes between weekend and weekday admissions, adjusting for over 30 covariates.

Main Results:

  • Weekend ADHF admissions were associated with increased odds of cardiac arrest (aOR: 1.10), inpatient mortality (aOR: 1.07), acute kidney injury (aOR: 1.07), and acute respiratory failure (aOR: 1.28).
  • No significant differences were found in mechanical circulatory support use or length of stay between weekend and weekday admissions.
  • The analysis included over 2.1 million ADHF hospitalizations, with 23.5% occurring on weekends.

Conclusions:

  • Weekend admissions for ADHF present a higher risk of mortality and complications.
  • Potential contributing factors include reduced specialist availability and delayed diagnostics on weekends.
  • Standardized ADHF care protocols are essential to mitigate disparities and ensure consistent quality of care throughout the week.