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Safety-First Framework for AI-Enabled Anamnesis in Head and Neck Surgery: Evidence Synthesis from a Narrative Review
Luigi Angelo Vaira1, Hareem Qadeer1,2, Jerome R Lechien3,4
1Maxillofacial Surgery Operative Unit, Department of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.
Journal of Clinical Medicine
|March 28, 2026
Summary
Artificial intelligence (AI) tools for medical history taking show varied results. While AI aids in structured data capture and reduces clinician burden, symptom checkers raise safety concerns, necessitating careful validation for head and neck surgery applications.
Area of Science:
- Medical Informatics
- Artificial Intelligence in Healthcare
- Head and Neck Surgery
Background:
- Artificial intelligence (AI) is increasingly explored for medical history taking (anamnesis).
- Existing research often focuses on large language models (LLMs), but a broader synthesis is needed.
- Understanding AI's role in head and neck surgery requires evaluating diverse applications beyond LLMs.
Purpose of the Study:
- To synthesize evidence on AI-enabled anamnesis, excluding LLM-only approaches.
- To identify implications and research priorities for head and neck surgery.
- To evaluate AI tools for history capture, summarization, interviewing, and triage.
Main Methods:
- A PRISMA-informed narrative review was conducted.
- Searches covered major databases (MEDLINE, Embase, Scopus, etc.) and preprint servers (medRxiv, arXiv).
- Included studies evaluated AI-supported history capture, conversational interviewing, symptom checkers, EHR integration, voice interviewing, training, and ethical considerations.
Main Results:
- Fifty studies (2014-2025) showed AI's feasibility and acceptability for pre-consultation history taking, reducing documentation burden.
- Symptom checkers and triage tools exhibited variable performance and safety concerns, requiring conservative escalation strategies.
- LLM-based dialogue showed promise in controlled settings, but real-world validation and integration are limited.
Conclusions:
- AI-enabled anamnesis tools are heterogeneous with inconsistent evidence.
- Near-term head and neck surgery applications include structured intake, clinician summarization, and training.
- Autonomous triage requires rigorous, specialty-specific validation and governance before clinical adoption.

