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[Polycystic disease of early infancy in two sisters (author's transl)]
Insights
Polycystic disease of early infancy is a rare genetic kidney disorder affecting both kidneys. Autosomal recessive inheritance is most likely, with no delayed manifestations observed in affected siblings.
Area of Science:
- Nephrology
- Medical Genetics
Background:
- Polycystic disease of early infancy is a heritable renal disorder.
- It presents diffusely in both kidneys without other renal malformations.
Abstract:
Polycystic disease of early infancy is a heritable disorder diffusely involving both kidneys with no other evidence of renal parenchymal malformation. After discussing the typical histological data of two sisters with normal family history a short survey about classification and differential diagnosis of similar heritable renal cysts is given. With regard to the few other cases with familiar occurrence an autosomal recessive transmission is the most likely form of inheritance, delayed manifestation has not been observed until now.