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A Predictive Bioengineering Model of Dental Implant Instability in Systemic Bone Disorders: A Periotest-Based
Liliana Sachelarie1, Ramona Feier2, Corina-Laura Ștefănescu3
1Department of Dental Medicine, Apollonia University, 700511 Iasi, Romania.
Bioengineering (Basel, Switzerland)
|March 28, 2026
Summary
Systemic bone disorders increase dental implant instability risk. A new bioengineering model using Periotest values predicts this risk, aiding early intervention for better patient outcomes.
Area of Science:
- Biomaterials Science
- Biomechanics
- Dental Implantology
Background:
- Dental implant instability is a dynamic process affected by bone stiffness and systemic health.
- Systemic bone disorders can compromise implant-bone interface stiffness, leading to undetected micromotion.
- Conventional clinical indicators may not detect instability in systemically compromised patients.
Purpose of the Study:
- To develop and validate a predictive bioengineering model for dental implant instability.
- To correlate dynamic Periotest measurements with systemic bone status and biomechanical instability.
- To provide a quantitative risk assessment framework for implant stability.
Main Methods:
- Retrospective analysis of 79 dental implants in patients with and without systemic bone disorders.
- Quantification of implant micromotion using Periotest values (PTVs).
- Application of linear and logistic regression, and a load-stiffness-micromotion framework.
Main Results:
- Implants in patients with systemic bone disorders showed significantly higher PTVs (+2.1 vs. -0.4).
- High-risk instability (PTV > +2.0) was found in 46% of the systemic group versus 9% of controls.
- Systemic bone disorders independently increased the odds of high-risk instability by 2.6-fold.
Conclusions:
- Dental implant instability in compromised patients stems from a load-stiffness imbalance.
- The predictive bioengineering model integrates dynamic PTVs, mechanical principles, and systemic status.
- This framework enables quantitative risk stratification beyond static stability assessments.

