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Updated: Mar 29, 2026
08:53
Visualizing Cellular Gibberellin Levels Using the nlsGPS1 Förster Resonance Energy Transfer (FRET) Biosensor
Published on: January 12, 2019
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Evolutionary Assembly and Future Design of Gibberellin Signaling
Weishu Fan1, Xihan Chen1,2, Dan Li1,3
1State Key Laboratory of Seed Innovation, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.
Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
|March 28, 2026
Summary
Plant hormone gibberellin (GA) signaling evolved stepwise, with key components like DELLA and GID1 integrating over time. This evolution enabled dynamic growth control and agricultural innovations but also revealed trade-offs, guiding future crop engineering.
Area of Science:
- Plant Biology
- Evolutionary Biology
- Molecular Biology
Background:
- Gibberellin (GA) signaling is a crucial plant growth pathway.
- Evidence suggests GA signaling evolved gradually, not as a pre-formed system.
Purpose of the Study:
- To explore the evolutionary origin and diversification of the GA signaling pathway.
- To understand how GA signaling integrates with other plant networks.
Main Methods:
- Comparative genomics analysis.
- Review of existing literature on GA pathway evolution.
- Analysis of DELLA-mediated growth repression and GID1 receptor emergence.
Main Results:
- DELLA-mediated growth repression predates GA hormone perception.
- The GA-GID1-DELLA module evolved for dynamic hormonal control.
- GA signaling evolution is linked to agricultural traits and trade-offs (e.g., plant height, nitrogen use efficiency).
Conclusions:
- The GA pathway's stepwise assembly enabled dynamic growth regulation and agricultural advancements.
- Understanding GA signaling's integration with metabolic and stress networks is key for crop improvement.
- Future research integrating AI and genomics can engineer climate-resilient crops.
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