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Updated: Mar 30, 2026

The Immersive Cleveland Clinic Virtual Reality Shopping Platform for the Assessment of Instrumental Activities of Daily Living

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Published on: July 28, 2022

Tracking the trail: Using VR to explore cognitive-motor function in Parkinson's disease.

Benedetta Heimler¹, Galina Berestetsky¹, Meytal Wilf^1,2

¹Center of Advanced Technologies in Rehabilitation, Sheba Medical Center, Tel Hashomer, Israel.

Neuropsychological Rehabilitation

|March 28, 2026

Summary

This summary is machine-generated.

A new virtual reality Color Trails Test (VR-CTT) assesses motor-cognitive interaction in Parkinson's disease (PD). This immersive tool shows unique motor difficulties during cognitive tasks, aiding diagnosis and rehabilitation.

Keywords:

Color Trails Test Parkinson’s disease cognitive-motor neurocognitive assessments virtual-reality

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Area of Science:

Neuroscience
Rehabilitation Medicine
Human-Computer Interaction

Background:

Cognitive impairments are common in Parkinson's disease (PD), often co-occurring with motor symptoms.
Current assessments typically evaluate motor and cognitive functions separately.
There is a need for integrated tools to understand motor-cognitive interactions in PD.

Purpose of the Study:

To evaluate the utility of a virtual reality-based Color Trails Test (VR-CTT) for assessing motor-cognitive interaction in individuals with PD.
To compare performance on the VR-CTT with a standard pen-and-paper version.
To explore the potential of VR-CTT for identifying specific motor deficits during cognitive tasks.

Main Methods:

A mixed-design study involving 23 individuals with PD and 23 healthy controls.
Participants completed both standard Color Trails Test (CTT) and VR-CTT.
Kinematic analysis was used to assess motor performance during the VR-CTT.

Main Results:

Individuals with PD showed slower and less accurate performance on both CTT formats.
Moderate-to-low correlations between standard CTT and VR-CTT suggest distinct performance aspects captured by VR-CTT.
Kinematic data revealed impaired head-hand coordination and reduced execution velocity in PD during cognitive tasks.

Conclusions:

The VR-CTT is a feasible and potentially valuable tool for assessing motor-cognitive performance in PD.
VR-CTT may offer insights into subtle motor deficits during cognitive engagement, complementing traditional assessments.
The immersive and integrated nature of VR-CTT suggests its potential for targeted cognitive-motor training in PD.