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Related Concept Videos

Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

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Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
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Atherosclerosis III: Management01:26

Atherosclerosis III: Management

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Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
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Related Experiment Video

Updated: Mar 30, 2026

Evaluation of a Novel Laser-assisted Coronary Anastomotic Connector - the Trinity Clip - in a Porcine Off-pump Bypass Model
12:00

Evaluation of a Novel Laser-assisted Coronary Anastomotic Connector - the Trinity Clip - in a Porcine Off-pump Bypass Model

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Complex Retrograde CTO-PCI With Laser Atherectomy and a Novel Tip-In Technique Into a Guide Catheter Extension.

Fatemeh Mohammed1, Manyoo A Agarwal1, Ronney Shantouf1

  • 1Heart Vascular Thoracic Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.

JACC. Case Reports
|March 28, 2026
PubMed
Summary

This study details a complex retrograde chronic total occlusion (CTO) percutaneous coronary intervention (PCI) using laser atherectomy and a novel tip-in microcatheter technique. These advanced methods successfully treated a challenging coronary artery blockage.

Area of Science:

  • Interventional Cardiology
  • Cardiovascular Medicine

Background:

  • Multivessel coronary artery disease presents complex treatment challenges.
  • Percutaneous coronary intervention (PCI) is an alternative for patients unsuitable for surgery.
Keywords:
NSTEMITrapLinercomplex-PCIlaser atherectomy

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  • Chronic total occlusions (CTOs) require advanced techniques for successful revascularization.