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Inferior turbinate reduction for refractory pediatric allergic rhinitis: Symptom control and sleep-related quality of
Jad Hosri1, Jonathan Abou Chaar1, Justin Ghadieh1
1Department of Otolaryngology - Head and Neck Surgery, American University of Beirut Medical Center, Beirut, Lebanon.
Insights
Inferior turbinate reduction surgery significantly improved symptom control and quality of life in children with refractory allergic rhinitis compared to medical therapy alone. This surgical intervention offers a better outcome for persistent allergic rhinitis symptoms.
Area of Science:
- Otolaryngology
- Allergy and Immunology
- Pediatric Surgery
Background:
- Allergic rhinitis is a common condition in children, often refractory to medical management.
- Persistent symptoms significantly impact quality of life, including sleep and sinonasal health.
- Inferior turbinate hypertrophy is a frequent finding in allergic rhinitis, contributing to nasal obstruction.
Purpose of the Study:
- To compare symptom control and quality of life in children with refractory allergic rhinitis.
- To evaluate outcomes between inferior turbinate reduction surgery and continued medical therapy.
- To assess sinonasal and sleep-related quality of life improvements in pediatric patients.
Main Methods:
- Prospective cohort pilot study involving children aged 5-17 years with refractory allergic rhinitis.
- Comparison between a surgical group (inferior turbinate reduction) and a medical therapy control group.
- Assessment using Sinus and Nasal-5 (SN-5), Obstructive Sleep Apnea-18 (OSA-18), and Nasal Obstruction Symptom Evaluation (NOSE) questionnaires at 1 and 3 months post-intervention.
Main Results:
- The surgical group showed statistically significant greater improvement in SN-5, OSA-18, and NOSE scores at 1 and 3 months compared to the medical group.
- Disease regression was significantly higher in the surgery group (88.2%) versus the medical group (29.4%) (p < 0.001).
- Improvements in all measured quality of life domains were significantly better with surgery.
Conclusions:
- Inferior turbinate reduction surgery is an effective treatment for children with refractory allergic rhinitis.
- Surgical intervention significantly improves symptom control and overall quality of life in this pediatric population.
- Turbinate reduction offers a valuable alternative for managing persistent allergic rhinitis symptoms impacting children's well-being.
Objective:
To compare symptom control, sinonasal and sleep-related quality of life in children with refractory allergic rhinitis treated with inferior turbinate reduction versus medical therapy.
Design:
This is a prospective cohort pilot study.
Population:
Children aged 5-17 years with a documented allergic rhinitis refractory to 3 months of medical therapy, were recruited. The study group consisted of children who underwent surgery and the control group included children who remained on medical therapy.
Primary Outcomes:
Three questionnaires pertaining to the sinus and nasal quality of life (SN-5), obstructive sleep apnea symptoms (OSA-18), and nasal obstruction symptom evaluation (NOSE) were collected before and after intervention at 1 and 3 months. Flexible endoscopic findings of disease regression before and after intervention were also mentioned.
Results:
Thirty-four subjects were recruited, 17 of whom underwent surgery and 17 who received medical therapy. At 1 month follow-up, the mean drop in the questionnaires' scores (SN-5; OSA-18; NOSE) was greater in the study group (9.9 ± 5.8; 23.2 ± 9.8, 8.2 ± 3.8, respectively) compared to the control group (6.8 ± 3.9, 17.3 ± 7.1, 4.6 ± 2.8, respectively). The difference in symptoms improvement between the two groups was a statistically significant in all three questionnaires (p = 0.029; p = 0.037; p = 0.005; respectively). Similar results were obtained at 3 months follow-up. Almost all patients in the surgery group (88.2%) had complete disease regression in comparison to only 29.4% in the control group (p < 0.001).
Conclusion:
Introducing surgery to children with refractory allergic rhinitis can significantly improve the patient's symptoms and quality of life.
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