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Updated: Mar 30, 2026

Smartphone Fundus Photography
Published on: July 6, 2017
Capturing Stereoscopic Three-Dimensional Images with a Cellphone Camera for Neuroanatomical Documentation: A
Alejandro Benjamin Romero Leguina1, Aluizio Alvarenga1, Mariano Teyssandier1
1Neurology and Neurosurgery, Universidade Federal de São Paulo, São Paulo, SP, Brazil.
Background And Objectives:
Three-dimensional visualization of neuroanatomy is essential for neurosurgical training, and stereoscopic photography remains a valuable educational tool. However, its use has traditionally depended on professional digital single-lens reflex (DSLR) cameras, limiting accessibility. Given recent advances in smartphones in imaging, these devices may represent a low-cost alternative for stereoscopic neuroanatomical documentation. This study aimed to describe a step-by-step protocol for capturing stereoscopic 3-dimensional images with a smartphone and to evaluate whether their perceptual quality differs from DSLR-based images.
Methods:
A standardized workflow was developed to obtain left and right images using a smartphone camera, maintaining fixed parameters for parallax, distance, lighting, and exposure. Images were aligned using freely available software and presented through polarized stereoscopic projection. Nine stereoscopic pairs representing a skull, surgical approaches, and a dissected brain were produced, and 9 additional pairs were obtained using a DSLR camera. Sixteen neurosurgeons evaluated the images using a 5-point Likert scale for sharpness, depth perception, and artifacts. Group differences were analyzed with the Wilcoxon Rank Sum Test and Cliff's Delta.
Results:
No statistically significant differences were found between smartphone and DSLR images for sharpness, depth perception, or artifacts (all P>0.05) and effect sizes were negligible (|δ|<0.14).
Conclusion:
To our knowledge, this is the first study to statistically compare stereoscopic neuroanatomical photographs acquired with a smartphone and a professional DSLR camera. Under standardized conditions, smartphones were able to produce stereoscopic images that were favorably rated by observers, while representing a substantially lower-cost and more accessible alternative.

