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Postoperative Writing Impairment in Glioma Patients Undergoing Awake Craniotomy
Tomoya Oishi1, Shinichiro Koizumi1, Dang Ngoc Phuong Dung1
1Department of Neurosurgery, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan.
World Neurosurgery
|March 29, 2026
Summary
Awake craniotomy for gliomas can impact language. This study found writing function may decline post-surgery, especially in younger patients, but improves over time.
Area of Science:
- Neurosurgery
- Neurology
- Oncology
Background:
- Awake craniotomy is standard for perisylvian gliomas to protect language.
- Perioperative language function assessment is crucial for these patients.
Purpose of the Study:
- To examine language impairment characteristics, including written language, in glioma patients undergoing awake surgery.
- To assess the impact of awake craniotomy on various language domains.
Main Methods:
- Retrospective analysis of 8 glioma patients undergoing awake craniotomy (April 2021-December 2024).
- Assessed Japanese language functions (speaking, listening, reading, writing) using the Standard Language Test for Aphasia (SLTA).
- Intraoperative object naming task used for mapping.
Main Results:
- Postoperative language function showed both improvement and decline, except for reading.
- Writing function declined in 3 of 5 patients with SLTA deficits.
- Younger patients and those without contrast-enhancing lesions trended toward writing deterioration, but all improved eventually.
Conclusions:
- Evaluating writing function is important alongside speech during awake mapping for gliomas.
- Attention to writing may improve language preservation and quality of life, particularly in specific patient groups.
