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Agentic AI for Prostate Cancer: A Vision for Multimodal Clinical Intelligence
N Papanikolaou1, A R Padhani2, F Sanguedolce3
1Clinical Computational Imaging Group, Champalimaud Research, Lisbon, Portugal.
European Urology Oncology
|March 29, 2026
Summary
Agentic AI systems are being developed to integrate diverse artificial intelligence (AI) tools for prostate cancer care. These systems aim to enhance clinical decision-making by synthesizing complex patient information more effectively.
Area of Science:
- Oncology
- Medical Informatics
- Artificial Intelligence
Background:
- Artificial intelligence (AI) shows promise in prostate cancer diagnostics and treatment planning.
- The integration of AI into routine clinical decision-making for prostate cancer remains limited.
- A need exists for tools that can effectively synthesize diverse clinical data to support oncologists.
Purpose of the Study:
- To introduce and describe the concept of Agentic AI systems.
- To highlight the role of Agentic AI systems as an orchestration layer for various AI agents.
- To propose Agentic AI systems as a solution for enhancing clinical decision-making in prostate cancer care.
Main Methods:
- Development of Agentic AI systems.
- Integration of multiple AI agents within an orchestration layer.
- Focus on synthesizing diverse clinical information for decision support.
Main Results:
- Agentic AI systems are conceptualized as a method to bridge the gap between AI advancements and clinical practice.
- These systems are designed to process and synthesize varied data inputs.
- The proposed systems aim to provide effective support for clinicians' decision-making processes.
Conclusions:
- Agentic AI systems represent a novel approach to leveraging AI in clinical oncology.
- Effective synthesis of clinical information is crucial for improving AI's impact on patient care.
- Further development of Agentic AI systems is expected to enhance clinical decision-making in prostate cancer management.

