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Related Concept Videos

Chronic Obstructive Pulmonary Disease01:24

Chronic Obstructive Pulmonary Disease

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COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
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Other Pulmonary Disorders01:17

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Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
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COPD: Pathogenesis and Clinical Features01:20

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Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
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Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

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Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
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COPD: Management Using Bronchodilators and Corticosteroids01:26

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Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
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Chronic Obstructive Pulmonary Disease-I: Introduction01:20

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Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
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Author Spotlight: Utilizing Traditional Chinese Acupuncture of the Ear to Improve Sleep Disorders
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Obstructive Sleep Apnea in Bronchiectasis: Prevalence, Risk Factors and Clinical Implications-A Systematic Review and

Narat Srivali1, Federica De Giacomi2

  • 1Division of Pulmonary, Allergy and Critical Care Medicine, Duke University School of Medicine, Durham, North Carolina, USA.

Journal of Sleep Research
|March 29, 2026
PubMed
Summary
This summary is machine-generated.

Obstructive sleep apnea (OSA) affects about half of bronchiectasis patients, a much higher rate than the general population. Screening is recommended, especially for males with longer disease duration or on corticosteroids.

Keywords:
bronchiectasismeta‐analysisobstructive sleep apneapolysomnographyprevalencesystematic review

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Area of Science:

  • Respiratory Medicine
  • Sleep Medicine

Background:

  • Obstructive sleep apnea (OSA) is poorly understood in bronchiectasis patients.
  • There are potential bidirectional clinical impacts between OSA and bronchiectasis.

Purpose of the Study:

  • To determine the prevalence of polysomnography-confirmed OSA in cystic fibrosis and non-cystic fibrosis bronchiectasis patients.

Main Methods:

  • Systematic review and meta-analysis of observational studies.
  • Searched MEDLINE, EMBASE, and Cochrane databases.
  • Included 5 studies with 256 adult bronchiectasis patients.

Main Results:

  • Pooled OSA prevalence was 50.5% (95% CI: 42.3%-58.9%).
  • Prevalence was similar in cystic fibrosis (40.4%-64.3%) and non-cystic fibrosis (40.8%-55.8%) bronchiectasis.
  • Male gender, longer disease duration, and corticosteroid use were significant risk factors; obesity and daytime sleepiness were weakly associated.
  • 16.7% experienced nocturnal hypoxemia independent of OSA.
  • Only 41% of diagnosed OSA patients received positive airway pressure therapy.

Conclusions:

  • OSA significantly impacts approximately half of all bronchiectasis patients, exceeding general population rates.
  • Clinical presentation differs from classical OSA, suggesting distinct pathophysiology.
  • Systematic OSA screening should be integrated into bronchiectasis management.