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Updated: Mar 31, 2026
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Microfluidic Flow Chambers Using Reconstituted Blood to Model Hemostasis and Platelet Transfusion In Vitro
Published on: March 19, 2016
10.1K
An innovative modelling proposal for the blood supply chain
Jorge Pagán-Ortiz1,2, Josué Pagán3,4, María Luisa Lozano1,5,6
1Medicine Department, University of Murcia, Murcia, Spain.
Vox Sanguinis
|March 29, 2026
Summary
Optimizing the blood transfusion chain requires a practical, vein-to-vein model. This approach identifies inefficiencies and streamlines processes from donation to recipient for better blood management and reduced shortages.
Area of Science:
- Transfusion Medicine
- Healthcare Systems Engineering
- Public Health
Background:
- Blood components for human use are obtained through whole-blood donation and apheresis.
- Existing blood donation systems face challenges in efficiency, waste reduction, donation rates, and shortages.
- Managing blood products with varying expiry dates presents significant storage and distribution hurdles.
Purpose of the Study:
- To identify inefficiencies within the blood transfusion chain.
- To propose a practical, renewed model for optimizing blood donation and management processes.
- To enhance the efficiency of blood component utilization and availability.
Main Methods:
- Analysis of 11 key processes across three periods: pre-donation, during donation, and post-processing.
- Development of a practical model focusing on streamlining existing donation procedures.
- Emphasis on a 'vein-to-vein' tracking system managed by a central data infrastructure.
Main Results:
- Identification of specific inefficiencies in the blood transfusion chain.
- A proposed model for optimizing processes before, during, and after blood donation.
- Highlighting the necessity of comprehensive 'vein-to-vein' tracking for system optimization.
Conclusions:
- A practical, integrated model can improve blood donation system efficiency.
- Streamlining processes and implementing comprehensive tracking are crucial for minimizing waste and shortages.
- Future work will focus on practical applications like scheduling and pre-donation haemoglobin monitoring.
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