Electrocardiographic Changes in Cholecystitis and Cholangitis
Daisuke Muroya1, Yuu Sasaki2, Daiki Miyazaki3
1Department of Emergency, Kitakyusyu City Yahata Hospital.
The Kurume Medical Journal
|March 29, 2026
Summary
Electrocardiogram (ECG) abnormalities are common in patients with cholecystitis and cholangitis. These changes, often T-wave abnormalities, are linked to disease severity and electrolyte imbalances, resolving with biliary disease treatment.
Area of Science:
- Cardiology
- Gastroenterology
- Internal Medicine
Background:
- Electrocardiographic (ECG) changes in biliary diseases like cholecystitis and cholangitis are infrequently documented.
- Detailed observational data on ECG abnormalities in these conditions are scarce.
Purpose of the Study:
- To determine the prevalence and characteristics of ECG abnormalities in patients with cholecystitis and cholangitis.
- To identify clinical factors associated with ECG changes in biliary disease.
Main Methods:
- Retrospective analysis of 402 hospitalized patients with biliary diseases.
- Included 79 cholecystitis and 111 cholangitis cases after exclusions.
- Evaluated ECG changes (T-wave, ST-segment, conduction blocks) and clinical variables.
Main Results:
- ECG abnormalities found in 43% of cholecystitis and 34% of cholangitis cases.
- T-wave abnormalities were most frequent, followed by ST-segment changes and conduction blocks.
- Associated factors included low potassium and high severity in cholecystitis; stroke history and high ALP in cholangitis.
Conclusions:
- Significant ECG abnormalities occur in patients with cholecystitis or cholangitis.
- Awareness is crucial for avoiding misdiagnosis and ensuring proper management.
- ECG changes normalized after treating the underlying biliary disease.
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