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Related Experiment Video

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Sleeve Gastrectomy in Mice using Surgical Clips
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Perinatal Outcomes After Sleeve Gastrectomy Compared to a Matched Control Group.

Amy Ngov1, James Elhindi2,3, Caron Blumenthal1

  • 1Department of Obstetrics and Gynaecology, Westmead Hospital, Western Sydney Local Health District, Sydney, New South Wales, Australia.

The Australian & New Zealand Journal of Obstetrics & Gynaecology
|March 30, 2026
PubMed
Summary

Pregnancy after sleeve gastrectomy (SG) is common, but outcomes vary. While SG reduces risks of gestational diabetes and hypertension, it increases the risk of small-for-gestational-age (SGA) infants, necessitating careful monitoring.

Keywords:
GDMSGApregnancysleeve gastrectomy

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Area of Science:

  • Bariatric surgery outcomes
  • Maternal-fetal medicine
  • Reproductive health

Background:

  • Pregnancy following sleeve gastrectomy (SG) is increasingly prevalent.
  • Limited data exists on perinatal outcomes after SG.
  • Understanding these outcomes is crucial for clinical management.

Purpose of the Study:

  • To compare perinatal outcomes in pregnancies after sleeve gastrectomy versus a matched non-bariatric control group.
  • To identify specific risks and benefits associated with pregnancy post-SG.
  • To inform clinical guidelines for managing pregnancies after bariatric surgery.

Main Methods:

  • Retrospective cohort study of 469 post-SG pregnancies and 915 matched controls (2016-2022).
  • Matching criteria included maternal age, pre-pregnancy BMI, parity, smoking, and delivery year.
  • Outcomes assessed included gestational diabetes, hypertension, infant size (LGA/SGA), perinatal mortality, preterm birth, neonatal admission, congenital anomalies, and caesarean births.

Main Results:

  • Post-SG pregnancies showed significantly lower rates of gestational diabetes (5.4% vs 16.6%), gestational hypertension/preeclampsia (1.1% vs 6.1%), large-for-gestational-age infants (6.0% vs 14.1%), and neonatal unit admission (13.9% vs 19.0%).
  • Conversely, pregnancies post-SG had a nearly doubled risk of small-for-gestational-age (SGA) infants (14.5% vs 8.3%).
  • A surgery-to-pregnancy interval under 12 months was linked to inadequate gestational weight gain but not other adverse outcomes.

Conclusions:

  • Pregnancy following sleeve gastrectomy is associated with an increased risk of small-for-gestational-age (SGA) infants, potentially due to nutrient deficiencies or unrecognized hypoglycemia.
  • Enhanced patient education, diligent nutrient monitoring and supplementation, and increased fetal surveillance are recommended for pregnancies post-SG.
  • These measures are vital for optimizing maternal and infant outcomes in this growing patient population.