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Updated: Mar 31, 2026

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Site-Specific Surface Modification via Chemoselective Click Reactions on Cyclobutene-Functionalized Monolayers

Boone W Evans1, Kenneth N Hipp1, William D Lambert1

  • 1Department of Chemistry, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.

Chemistryopen
|March 30, 2026
PubMed
Summary

This study introduces self-assembled monolayers with cyclobutene for surface modification. These monolayers enable efficient chemical reactions, allowing for controlled bisfunctionalization via Diels-Alder and click chemistry.

Keywords:
clickcyclobuteneelectrochemical sensinginverse electron‐demand Diels–Alderself‐assembled monolayers

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