Comparative Effectiveness of Myopia-control Spectacle Lenses: Clincial setting Performance from a Retrospective...

Area of Science:

• Ophthalmology
• Pediatric Optometry
• Myopia Control Research

Background:

• Myopia is a growing public health concern in children.
• Effective myopia control strategies are crucial to prevent high myopia and associated ocular complications.
• Spectacle lenses offer a non-invasive approach to myopia management.

Purpose of the Study:

• To compare the clinical effectiveness of three myopia control spectacle lenses: defocus incorporated multiple segments (DIMS), highly aspherical lenslet target (HALT), and cylindrical annular refractive elements (CARE).
• To evaluate their efficacy in attenuating axial elongation and myopic refractive shift in children compared to single-vision lenses (SVLs).

Main Methods:

• A retrospective cohort study involving 899 children (aged 6-16 years) with myopia.
• Subjects were prescribed either SVLs, DIMS, HALT, or CARE lenses.
• Longitudinal changes in axial length (AL) and spherical equivalent (SE) refraction were analyzed using linear mixed-effects models.

Main Results:

• All myopia control lenses (DIMS, HALT, CARE) significantly slowed axial elongation compared to SVLs.
• HALT lenses demonstrated the greatest efficacy in slowing AL elongation (0.054 mm/year) compared to DIMS (0.098 mm/year) and CARE (0.088 mm/year).
• All myopia control lenses also significantly reduced myopic SE progression, with HALT showing the lowest rate (-0.073 D/year).

Conclusions:

• Highly aspherical lenslet target (HALT), DIMS, and CARE lenses are effective in slowing myopia progression in children compared to SVLs.
• HALT lenses appear to offer superior control of axial elongation.
• Further prospective studies are recommended to confirm these findings and explore optimal myopia management strategies.