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Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain
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Trigeminal Nerve Blocks for Medically Intractable Painful Trigeminal Neuropathy
You-Chia Chen1,2, Hsinlin Thomas Cheng2
1Department of Neurology, Cathay General Hospital, Taipei, Taiwan, Republic of China.
Journal of Pain Research
|March 30, 2026
Summary
Trigeminal nerve blocks (TNB) effectively reduced pain in 81.1% of patients with painful trigeminal neuropathy (PTN). Steroids combined with local anesthetics in TNB showed promising outcomes for managing this condition.
Area of Science:
- Neurology
- Pain Management
- Anesthesiology
Background:
- Painful trigeminal neuropathy (PTN) is a severe condition causing persistent facial pain after nerve injury.
- It often resists medication and significantly impacts quality of life.
- Trigeminal nerve blocks (TNB) are explored as a treatment option.
Purpose of the Study:
- To evaluate the efficacy of trigeminal nerve blocks (TNB) for patients diagnosed with painful trigeminal neuropathy (PTN).
- To identify factors influencing the success and duration of pain relief from TNB.
- To assess the role of local anesthetics and steroid co-administration in TNB outcomes.
Main Methods:
- Retrospective chart review of 90 PTN patients who underwent TNB.
- Analysis of TNB procedures involving various local anesthetic combinations (lidocaine, ropivacaine, bupivacaine).
- Investigation of triamcinolone co-administration and its contraindications.
Main Results:
- 81.1% of patients experienced at least 50% pain reduction.
- Pain relief duration varied, with 50% reporting relief for ≥6 weeks.
- Effective regimens included combinations of local anesthetics with triamcinolone.
Conclusions:
- Trigeminal nerve blocks (TNB) with local anesthetics and steroids demonstrate efficacy in managing painful trigeminal neuropathy (PTN).
- Factors like depression, maxillary nerve involvement, and facial numbness may indicate poorer prognostic outcomes.
- TNB offers a viable therapeutic strategy for refractory PTN.
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