Role of digital triradius variants and hypothenar patterns in early screening of primary amenorrhea

Dermatoglyphics, the study of epidermal ridge patterns, is associated with various genetic disorders. Primary amenorrhea, a condition with multifactorial and often genetic etiology, may show distinct dermatoglyphic traits. Hence, the 'ATD' angle was measured in 40 females with primary amenorrhea and 60 healthy controls. Data revealed significantly higher mean 'ATD' angles and greater right-left asymmetry in cases compared to controls. Thus, we show that dermatoglyphic analysis, particularly of the 'ATD' angle, can serve as a simple, non-invasive screening tool for identifying individuals at risk of genetic abnormalities in primary amenorrhea.