Effect of I-PRF and alloplastic bone material in periodontal osseous defects - A case series

Periodontal regeneration in patients with chronic periodontitis remains a clinical challenge due to limited predictability of current regenerative materials and techniques. This case series was conducted on 10 patients diagnosed with moderate to advanced chronic periodontitis. Participants received i-PRF with Hydroxyapatite bone graft. Clinical parameters and radiographic bone defect depth were measured at baseline and after 6 months. Following surgical intervention, patients exhibited greater reductions in PPD, gains in CAL and increased bone fill suggesting that i-PRF may enhance periodontal regeneration when used in conjunction with alloplastic bone grafts.