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Related Concept Videos

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Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
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Related Experiment Video

Updated: Mar 31, 2026

Generation and Quantitative Characterization of Functional and Polarized Biliary Epithelial Cysts
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Radiologic-Pathologic Correlation in Biliary Cystic Neoplasms: Insights From a Single-Centre Experience.

Evangelia Florou1, Rakshana Munusamy1, Memoona Mukhtar1

  • 1Hepato-Pancreato-Biliary Surgery, King's College Hospital, London, GBR.

Cureus
|March 30, 2026
PubMed
Summary
This summary is machine-generated.

Differentiating benign biliary cystadenomas (BCAs) from malignant biliary cystadenocarcinomas (BCACs) preoperatively is difficult. Imaging features like wall enhancement suggest malignancy in biliary cystic neoplasms (BCNs), but overlap with benign lesions limits accuracy.

Keywords:
biliary cystadenocarcinomabiliary cystadenomabiliary cystic neoplasmhepatic cystic lesionmriradiologic–pathologic correlation

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A Coregistered Ultrasound and Photoacoustic Imaging Protocol for the Transvaginal Imaging of Ovarian Lesions
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Area of Science:

  • Hepatobiliary Medicine
  • Gastroenterology
  • Radiology

Background:

  • Biliary cystic neoplasms (BCNs), including biliary cystadenomas (BCAs) and cystadenocarcinomas (BCACs), are rare liver and biliary tract tumors.
  • Preoperative differentiation between benign and malignant BCNs is challenging due to limitations in current imaging criteria.

Purpose of the Study:

  • To correlate preoperative imaging features with final histology in BCNs.
  • To identify radiologic markers for malignancy in BCNs.

Main Methods:

  • Retrospective analysis of 42 histologically confirmed BCN cases (2010-2023).
  • Review of preoperative cross-sectional imaging (CT/MRI/MRCP) for features like wall enhancement, septations, mural nodules, calcification, and fluid complexity.
  • Histological categorization into low-grade dysplasia (LGD), high-grade dysplasia (HGD), or invasive carcinoma (BCAC).

Main Results:

  • Wall enhancement was more frequent in advanced histology (67%) versus LGD (28%).
  • Thick fluid density correlated with advanced pathology (33% vs. 8%).
  • Mural nodules were only found in LGD cases, not in HGD or BCAC.

Conclusions:

  • Wall enhancement and complex fluid are suggestive of advanced BCN but have limited diagnostic accuracy due to overlap with benign lesions.
  • Mural nodules were not predictive of malignancy in this cohort.
  • Surgical resection of complex or atypical cystic liver lesions is recommended; multidisciplinary consensus and histologic evaluation are crucial for diagnosis.