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Updated: Sep 5, 2026

Cellular Lipid Extraction for Targeted Stable Isotope Dilution Liquid Chromatography-Mass Spectrometry Analysis
Published on: November 17, 2011
[Progestagen and contraceptive activity of a 16alpha-methylene derivative of progesterone]
Abstract:
Data of experimental character reflecting the pharmacological activity of 16alpha-methylene derivative of progesterone--melengesterol acetate--are presented. A high progestagenic activity of the preparation was revealed in a series of tests, namely, the appearance of secretory changes in the uterine endometrium of infantile female rabbits and persistence of pregnancy in ovariectomized rabbits. A high contraceptive activity not accompanied by suppression of ovulation was found in administration of the preparation in low doses combined with mestranol.
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