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Radiotherapy for Refractory Cystic Progression in Basal Ganglia Pilocytic Astrocytoma: A Case Report
Shohei Nagasaka1, Kohei Suzuki1, Takeshi Saito1
1Neurosurgery, University of Occupational and Environmental Health, Kitakyushu, JPN.
Cureus
|March 30, 2026
Summary
Pilocytic astrocytoma (PA) with protein-rich cysts poses management challenges. Fractionated radiotherapy proved effective for a refractory cystic PA case, stabilizing the lesion without adverse events.
Area of Science:
- Pediatric neuro-oncology
- Neurosurgery
- Radiation oncology
Background:
- Pilocytic astrocytoma (PA) is a common pediatric low-grade glioma, frequently presenting with cystic components.
- Management of cystic PA can be difficult, especially in deep locations or when associated with highly proteinaceous cyst fluid.
- Conventional treatments like surgery and CSF diversion may fail in refractory cases.
