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High- and Low-Dose Oral Sesame Immunotherapy: Interim Analysis of a Randomized Single-Center Open-Label Trial
Joanna Zielińska1, Anna Krupa-Łaska1, Marek Kulus1
1Department of Paediatric Pulmonology and Allergology, Medical University of Warsaw, Warsaw, Poland.
Journal of Asthma and Allergy
|March 30, 2026
Summary
This study found that both low and high doses of sesame oral immunotherapy (OIT) are effective and safe for children with sesame allergy, showing similar results in tolerance and immune responses. Further research is needed to confirm optimal dosing strategies for sesame OIT.
Area of Science:
- Allergy and Immunology
- Pediatric Gastroenterology
- Clinical Trials
Background:
- Sesame allergy affects a significant pediatric population.
- Oral immunotherapy (OIT) is a promising treatment for food allergies.
- Optimal maintenance dosing for sesame OIT requires further investigation.
