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lncRNA ch-MYC-AS1 restricts ALV-J replication by disrupting the ANXA2-C-Myc oncogenic axis

Suyu Fan1,2, Weiyi Zhou3, Xuming Hu1,2

  • 1Jiangsu Key Laboratory for Animal Genetic, Breeding and Molecular Design, College of Animal Science and Technology, Yangzhou University, Yangzhou, Jiangsu, China.

Microbiology Spectrum
|March 30, 2026
PubMed
Summary

A novel long noncoding RNA, ch-MYC-AS1, inhibits avian leukosis virus subgroup J (ALV-J) replication. It targets the c-Myc/ANXA2 pathway, offering a potential strategy against retroviral infections and MYC-driven cancers.

Keywords:
ANXA2avian leukosis virusch-MYC-AS1oncogenic retrovirus

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