Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cancer Cell Migration through Invadopodia01:35

Cancer Cell Migration through Invadopodia

Invadosome is a broad category of cell surface structures with proteolytic activity that  degrades the extracellular matrix (ECM). Invadosomes are present in normal cell types, including macrophages, endothelial cells, and neurons, as well as tumor cells. Although the macrophage podosomes and tumor cell invadopodia are classified as invadosomes, they have different structures, molecular pathways, and functions. Podosomes are short structures that last for a few minutes. However, invadopodia can...
Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...
Papillary Dermis01:11

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Diabetic Foot Ulcer01:31

Diabetic Foot Ulcer

Definition A diabetic foot ulcer (DFU) is a chronic, non-healing wound that develops in individuals with diabetes. It typically occurs on pressure-bearing areas such as the heel, metatarsal heads, or hallux, and carries a high risk of infection and amputation.Pathophysiology • The development of DFUs can be explained by four interconnected mechanisms: neuropathy, ischemia, infection, and impaired wound healing. • Neuropathy is the most common factor. Sensory neuropathy reduces pain perception,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Artificial Intelligence in Hospice and Palliative Care: A Systematic Review of Its Role in Interprofessional Shared Decision-Making Care.

The American journal of hospice & palliative care·2026
Same author

Altered crosstalk of bacterial lipopolysaccharide with immune cells in colorectal cancer compared to paired adjacent intestinal tissue.

Gut microbes·2026
Same author

Transmigrated neutrophils on the ocular surface and in other tissues: A narrative review.

The ocular surface·2026
Same author

Nodular fasciitis in unusual (and usual) locations: lessons learned from a challenging diagnosis.

Pathology·2026
Same author

[Hidradenitis Suppurativa: Most Relevant Epidemiological Characteristics of an Underdiagnosed Disease. A Cross-Sectional Study]

Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina)·2025
Same author

Primary extramedullary plasmacytoma: a rare case presentation.

Anais brasileiros de dermatologia·2025

Related Experiment Video

Updated: Jun 29, 2026

Murine Experimental Model of Original Tumor Development and Peritoneal Metastasis via Orthotopic Inoculation with Ovarian Carcinoma Cells
08:17

Murine Experimental Model of Original Tumor Development and Peritoneal Metastasis via Orthotopic Inoculation with Ovarian Carcinoma Cells

Published on: December 9, 2016

[Eccrine porocarcinoma on the dorsum of the foot: case report of a rare tumor]

Juana Sanguinetti1, Lía Salomé Abeledo1, María Walker1

  • 1Hospital Universitario Austral.

Revista De La Facultad De Ciencias Medicas (Cordoba, Argentina)
|March 30, 2026
PubMed
Summary
This summary is machine-generated.

Eccrine porocarcinoma is a rare but aggressive malignant skin tumor. This case highlights an unusual foot presentation, emphasizing integrated diagnosis and complete surgical excision for optimal outcomes.

Keywords:
eccrine porocarcinomaporomacarcinoma, skin appendage

More Related Videos

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
09:37

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition

Published on: August 18, 2022

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
06:15

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Related Experiment Videos

Last Updated: Jun 29, 2026

Murine Experimental Model of Original Tumor Development and Peritoneal Metastasis via Orthotopic Inoculation with Ovarian Carcinoma Cells
08:17

Murine Experimental Model of Original Tumor Development and Peritoneal Metastasis via Orthotopic Inoculation with Ovarian Carcinoma Cells

Published on: December 9, 2016

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
09:37

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition

Published on: August 18, 2022

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
06:15

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Area of Science:

  • Dermatology
  • Oncology
  • Pathology

Background:

  • Eccrine porocarcinoma is a rare adnexal tumor with metastatic potential.
  • Typically affects elderly individuals, often on the head and neck.
  • Presents clinically as a solitary, nodular, erythematous-violaceous lesion.

Purpose of the Study:

  • To report a case of eccrine porocarcinoma in an unusual location.
  • To analyze the diagnostic and therapeutic approach for this rare malignancy.

Main Methods:

  • Clinical presentation and physical examination of a 59-year-old male patient.
  • Dermatoscopy revealed erythematous and whitish areas.
  • Incisional biopsy with histopathological and immunohistochemical analysis (EMA, CEA, p63).
  • Complete surgical excision with clear margins.

Main Results:

  • Histopathology confirmed eccrine porocarcinoma in situ arising from a poroma.
  • Immunohistochemistry supported the diagnosis.
  • The patient underwent complete excision with free margins.
  • No recurrence was observed at the time of reporting.

Conclusions:

  • Eccrine porocarcinoma is a rare but aggressive cutaneous neoplasm.
  • Diagnosis requires a comprehensive approach integrating clinical, histopathological, and immunohistochemical findings.
  • Complete surgical excision with clear margins is the primary treatment; adjuvant therapies may be considered for advanced cases.
  • Regular follow-up is crucial for early detection of recurrence and metastasis.