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Updated: Apr 1, 2026

A Practical Guide for the Production and PET/CT Imaging of 68Ga-DOTATATE for Neuroendocrine Tumors in Daily Clinical Practice
Published on: April 17, 2019
Incidental Left Ventricular Myocardial Uptake of 68 Ga-NODAGA-JR11 in a Patient With Neuroendocrine Tumor
Mehul Taggar1, Sanjeev Kumar2, Mayank Goyal2
1Departments of Nuclear Medicine.
68 Ga-labeled somatostatin receptor (SSTR) antagonists such as 68 Ga-NODAGA-JR11 are increasingly used for imaging neuroendocrine tumors (NETs) owing to their higher lesion detection rates compared with agonists. Incidental findings on these scans can occasionally provide unexpected insights. We report a patient with NET who demonstrated diffuse uptake of 68 Ga-NODAGA-JR11 in the left ventricular myocardium. This unusual finding raises considerations regarding non-tumor binding sites of SSTR antagonists and their potential physiological or pathologic correlates. Awareness of such uptake patterns is essential to avoid misinterpretation.
68 Ga-labeled somatostatin receptor (SSTR) antagonists such as 68 Ga-NODAGA-JR11 are increasingly used for imaging neuroendocrine tumors (NETs) owing to their higher lesion detection rates compared with agonists. Incidental findings on these scans can occasionally provide unexpected insights. We report a patient with NET who demonstrated diffuse uptake of 68 Ga-NODAGA-JR11 in the left ventricular myocardium. This unusual finding raises considerations regarding non-tumor binding sites of SSTR antagonists and their potential physiological or pathologic correlates. Awareness of such uptake patterns is essential to avoid misinterpretation.
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