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Collagenous Fibroma With Metaplastic Ossification in the Periocular Region
Jeeyoon Kim1, Yerin Kim, Jongweon Shin
1Department of Plastic and Reconstructive Surgery, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
The Journal of Craniofacial Surgery
|March 30, 2026
Summary
Collagenous fibroma is a rare benign tumor. This case highlights a periocular collagenous fibroma with ossification that mimicked aggressive lesions, emphasizing the need for accurate diagnosis.
Area of Science:
- Oncology
- Pathology
- Ophthalmology
Background:
- Collagenous fibroma is a rare benign soft-tissue tumor.
- Periocular involvement is exceptionally uncommon.
- Metaplastic ossification within this tumor is rarely reported and can complicate diagnosis.
Purpose of the Study:
- To describe a rare case of collagenous fibroma with ossification in the periocular region.
- To highlight the diagnostic challenges posed by this entity.
- To emphasize the importance of recognizing benign lesions that mimic aggressive tumors.
Main Methods:
- Case report of a 49-year-old woman with a periocular mass.
- Magnetic resonance imaging (MRI) for lesion characterization.
- Histopathologic examination for definitive diagnosis.
Main Results:
- MRI revealed a well-circumscribed lesion with low signal intensity, raising concerns for other fibrous or osseous tumors.
- Histopathology confirmed a collagenous fibroma with metaplastic ossification.
- Complete local excision was curative with no recurrence.
Conclusions:
- Periocular collagenous fibroma with ossification can mimic more aggressive lesions.
- Accurate diagnosis is crucial to avoid diagnostic confusion and unnecessary aggressive management.
- This benign entity should be recognized in the differential diagnosis of periocular masses.
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