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Biopesticides offer a sustainable alternative to chemical pesticides, utilizing microbial agents to control agricultural pests. Bacillus thuringiensis (Bt) is a widely employed bacterium known for its potent insecticidal activity. Bt biopesticides are favored for their specificity to insect pests, minimal environmental impact, and natural degradability.Mechanism of Bt Toxin Action Bt produces insecticidal crystal (Cry) proteins during its sporulation phase. These proteins form parasporal...

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Updated: Apr 1, 2026

Double-stranded RNA Oral Delivery Methods to Induce RNA Interference in Phloem and Plant-sap-feeding Hemipteran Insects

Double-stranded RNA Oral Delivery Methods to Induce RNA Interference in Phloem and Plant-sap-feeding Hemipteran Insects

Published on: May 4, 2018

Fusion protein based strategies for developing insect-resistant crops.

Marri Keerthana¹, Morthala Shankara Sai Reddy², Yogesh Dashrath Naik^3,4

¹PG College of Agriculture, Dr. Rajendra Prasad Central Agricultural University, Pusa, Samastipur, Bihar, 848125, India.

Functional & Integrative Genomics

|March 30, 2026

Summary

This summary is machine-generated.

Developing fusion proteins offers a sustainable solution for insect pest control in crops. These engineered molecules target pests effectively, overcoming pesticide resistance and protecting beneficial insects and the environment.

Keywords:

Fusion proteins Insect resistance Scorpion toxins Single gene constructs Spider venom Transgenic crops

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Functional Characterization of Carboxylesterases in Insecticide Resistant House Flies, Musca Domestica

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Functional Characterization of Carboxylesterases in Insecticide Resistant House Flies, Musca Domestica

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Published on: August 23, 2018

Area of Science:

Agricultural Science
Biotechnology
Entomology

Background:

Chemical pesticides cause environmental harm and pesticide resistance.
Integrated Pest Management (IPM) requires sustainable pest control methods.
Conventional breeding for pest resistance is slow and complex.

Purpose of the Study:

To review fusion protein technology for insect pest control in crops.
To highlight fusion proteins as an alternative to traditional pesticides.
To discuss the application of fusion proteins in developing insect-resistant transgenic crops.

Main Methods:

Review of scientific literature on fusion protein technology.
Analysis of fusion protein applications in crop plants.
Discussion of advantages over single-gene constructs.

Main Results:

Fusion proteins effectively target specific insect pests.
Engineered molecules overcome limitations of single-gene resistance.
Successful deployment in various crops demonstrates broad-spectrum activity.

Conclusions:

Fusion proteins represent a versatile and effective biotechnological approach for insect pest management.
This technology enhances crop resistance, reduces pesticide reliance, and supports ecological balance.
Further development and application of fusion proteins are crucial for sustainable agriculture.