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Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression
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Examining Suicidal Ideation and Capability Across the Menstrual Cycle.

Keyne C Law1, Katherine L O'Connell1, Jordan C Barone2

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Summary

Fearlessness about death (FAD) did not change across the menstrual cycle. However, FAD was linked to daily mood changes and passive suicidal ideation in women with a history of suicidal thoughts.

Keywords:
capability for suicidefearlessness about deathmenstrual cyclesuicide

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Area of Science:

  • Psychiatry
  • Reproductive Endocrinology
  • Behavioral Neuroscience

Background:

  • Suicidal thoughts and behaviors are linked to menstrual cycle phases.
  • The study investigated fearlessness about death (FAD) across the menstrual cycle.
  • Previous research suggests connections between the menstrual cycle and suicidal ideation.

Purpose of the Study:

  • To determine if fearlessness about death (FAD) fluctuates across the menstrual cycle.
  • To explore the relationship between FAD and suicidal behavior correlates throughout the cycle.

Main Methods:

  • 46 women with natural menstrual cycles and past-month suicidal ideation participated.
  • Daily ratings of FAD and suicidal ideation were collected over two months.
  • Menstrual cycle phases were self-reported.

Main Results:

  • Fearlessness about death (FAD) remained stable and did not vary significantly by cycle day or phase.
  • FAD showed significant associations with daily depression, anger, irritability, and passive suicidal ideation.

Conclusions:

  • Affective states, not ovarian hormones, appear to influence FAD in women with suicidal ideation.
  • Strict inclusion criteria may have limited the detection of FAD fluctuations.