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Related Concept Videos

Case Studies01:22

Case Studies

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There are many research methods available to psychologists in their efforts to understand, describe, and explain behavior and the cognitive and biological processes that underlie it.
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Case 348.

Noushin Yahyavi-Firouz-Abadi1

  • 1Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, 22 S Greene St, Baltimore, MD 21201.

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|March 31, 2026
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Summary
This summary is machine-generated.

A child with sickle cell disease experienced eye swelling and pain, indicating a potential complication. Prompt imaging confirmed orbital involvement, highlighting the need for vigilant monitoring in these patients.

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Area of Science:

  • Pediatric Hematology
  • Ophthalmology
  • Radiology

Background:

  • Sickle cell disease (SCD) is a genetic blood disorder associated with various complications.
  • Acute chest syndrome is a common SCD complication, but orbital involvement is less frequently reported.
  • Early recognition of SCD complications is crucial for timely intervention.

Purpose of the Study:

  • To report a case of orbital complication in a child with sickle cell disease.
  • To highlight the diagnostic utility of advanced imaging in evaluating such cases.
  • To emphasize the importance of considering SCD complications in pediatric patients presenting with relevant symptoms.

Main Methods:

  • Case report of a 6-year-old boy with SCD and acute chest syndrome.
  • Clinical presentation included right eye swelling, pain, and elevated inflammatory markers.
  • Diagnostic imaging included contrast-enhanced CT of the face and MRI of the brain and orbits.

Main Results:

  • Physical examination revealed right eye swelling and erythema.
  • Laboratory tests showed anemia, elevated white blood cell count, and elevated liver enzymes.
  • Imaging confirmed orbital involvement, consistent with a complication of sickle cell disease.

Conclusions:

  • Orbital complications can occur in children with sickle cell disease, even after acute chest syndrome.
  • Advanced imaging like CT and MRI are essential for diagnosing orbital involvement in SCD.
  • Prompt diagnosis and management are critical to prevent long-term sequelae.